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21 April 2016 Physico-chemical and biochemical approaches to assessing the development of precancerous pathologies of the gastrointestinal tract during their modeling in mice with complex effects of stress factors of different nature
Zamira O. Alieva, Matvej V. Kanevskiy, Anna A. Galitskaya, Irina K. Mironova, Ekaterina V. Pleshakova, Vladimir A. Velikov, Daniil S. Chumakov, Oxana V. Semyachkina-Glushkovskaya, Svetlana A. Konnova
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Proceedings Volume 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS); 99170C (2016) https://doi.org/10.1117/12.2225478
Event: Saratov Fall Meeting 2015, 2015, Saratov, Russian Federation
Abstract
It was shown in the experience with 60 white mice that separate and combined effects of stress factors: noctidial lighting (800 lux), sodium nitrite (0.2% solution in water) and p-toluidine (with food) within 107 days causes a change in impedance value of erythrocytes at frequencies 1 Hz – 1MHz. Changes in the activity of intracellular aminotransferases, creatinine and urea were observed, indicating cardiotoxic and hepatotoxic effects.
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Zamira O. Alieva, Matvej V. Kanevskiy, Anna A. Galitskaya, Irina K. Mironova, Ekaterina V. Pleshakova, Vladimir A. Velikov, Daniil S. Chumakov, Oxana V. Semyachkina-Glushkovskaya, and Svetlana A. Konnova "Physico-chemical and biochemical approaches to assessing the development of precancerous pathologies of the gastrointestinal tract during their modeling in mice with complex effects of stress factors of different nature", Proc. SPIE 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS), 99170C (21 April 2016); https://doi.org/10.1117/12.2225478
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KEYWORDS
Stomach
Blood
Cancer
NOx
Pathology
Urea
Chemical analysis
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