In situ monitoring of biomolecular processes in living systems using surface-enhanced Raman scattering

Mine Altunbek; Seda Kelestemur; Mustafa Culha

doi:10.1117/12.2207321

9 December 2015 In situ monitoring of biomolecular processes in living systems using surface-enhanced Raman scattering

Mine Altunbek, Seda Kelestemur, Mustafa Culha

Proceedings Volume 9792, Biophotonics Japan 2015; 979206 (2015) https://doi.org/10.1117/12.2207321
Event: SPIE/OSJ Biophotonics Japan, 2015, Tokyo, Japan

Abstract

Surface-enhanced Raman scattering (SERS) continues to strive to gather molecular level information from dynamic biological systems. It is our ongoing effort to utilize the technique for understanding of the biomolecular processes in living systems such as eukaryotic and prokaryotic cells. In this study, the technique is investigated to identify cell death mechanisms in 2D and 3D in vitro cell culture models, which is a very important process in tissue engineering and pharmaceutical applications. Second, in situ biofilm formation monitoring is investigated to understand how microorganisms respond to the environmental stimuli, which inferred information can be used to interfere with biofilm formation and fight against their pathogenic activity.

Citation Download Citation

Mine Altunbek, Seda Kelestemur, and Mustafa Culha "In situ monitoring of biomolecular processes in living systems using surface-enhanced Raman scattering", Proc. SPIE 9792, Biophotonics Japan 2015, 979206 (9 December 2015); https://doi.org/10.1117/12.2207321

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