A wearable conformal bandage for non-invasive two-dimensional imaging of skin oxygenation
(Conference Presentation)

Zongxi Li; Emmanuel Roussakis; Emily Keeley; Gabriela Apiou-Sbirlea; Reginald Birngruber; Christene Huang; Conor L. Evans

doi:10.1117/12.2211887

27 April 2016 A wearable conformal bandage for non-invasive two-dimensional imaging of skin oxygenation (Conference Presentation)

Zongxi Li, Emmanuel Roussakis, Emily Keeley, Gabriela Apiou-Sbirlea, Reginald Birngruber, Christene Huang, Conor L. Evans

Author Affiliations +

Proceedings Volume 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics; 97150R (2016) https://doi.org/10.1117/12.2211887
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

The complex surface topology and soft mechanics of the skin poses a considerable challenge to the development of wearable, conformal sensors. As a results, current clinical assessments of healing-related skin parameters often rely on bulky and expensive optical systems that are difficult to deploy at the point of care. Here, using a rapid-drying, liquid bandage containing oxygen-sensing molecules, we created a wearable sensor bandage that conforms the surface geometry of skin and wounds, and provides two-dimensional maps of cutaneous oxygenation in a non-disruptive fashion. Custom oxygen sensing phosphors have been developed in house that are at least five times brighter than the commercial sensing molecules, enabling the visualization of oxygen concentration using a simple color camera or even by eye under ambient lighting conditions. The oxygen-sensing bandage has been applied to monitor tissue ischemia, graft integration, as well as the progression of burn in animal models. Recent studies have demonstrated its ability to track and quantify skin inflammation induced by complete Freund’s adjuvant in an in vivo porcine model.

Conference Presentation

Citation Download Citation

Zongxi Li, Emmanuel Roussakis, Emily Keeley, Gabriela Apiou-Sbirlea, Reginald Birngruber, Christene Huang, and Conor L. Evans "A wearable conformal bandage for non-invasive two-dimensional imaging of skin oxygenation (Conference Presentation)", Proc. SPIE 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, 97150R (27 April 2016); https://doi.org/10.1117/12.2211887

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