Optical fiber biocompatible sensors for monitoring selective treatment of tumors via thermal ablation

Daniele Tosi; Sven Poeggel; Duraibabu B. Dinesh; Edoardo G. Macchi; Mario Gallati; Giovanni Braschi; Gabriel Leen; Elfed Lewis

doi:10.1117/12.2192201

28 September 2015 Optical fiber biocompatible sensors for monitoring selective treatment of tumors via thermal ablation

Daniele Tosi, Sven Poeggel, Duraibabu B. Dinesh, Edoardo G. Macchi, Mario Gallati, Giovanni Braschi, Gabriel Leen, Elfed Lewis

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Proceedings Volume 9634, 24th International Conference on Optical Fibre Sensors; 963428 (2015) https://doi.org/10.1117/12.2192201
Event: International Conference on Optical Fibre Sensors (OFS24), 2015, Curitiba, Brazil

Abstract

Thermal ablation (TA) is an interventional procedure for selective treatment of tumors, that results in low-invasive outpatient care. The lack of real-time control of TA is one of its main weaknesses. Miniature and biocompatible optical fiber sensors are applied to achieve a dense, multi-parameter monitoring, that can substantially improve the control of TA. Ex vivo measurements are reported performed on porcine liver tissue, to reproduce radiofrequency ablation of hepatocellular carcinoma. Our measurement campaign has a two-fold focus: (1) dual pressure-temperature measurement with a single probe; (2) distributed thermal measurement to estimate point-by-point cells mortality.

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Daniele Tosi, Sven Poeggel, Duraibabu B. Dinesh, Edoardo G. Macchi, Mario Gallati, Giovanni Braschi, Gabriel Leen, and Elfed Lewis "Optical fiber biocompatible sensors for monitoring selective treatment of tumors via thermal ablation", Proc. SPIE 9634, 24th International Conference on Optical Fibre Sensors, 963428 (28 September 2015); https://doi.org/10.1117/12.2192201

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KEYWORDS

Radiofrequency ablation

Sensors

Tumors

Temperature metrology

Optical fibers

Tissues

Fiber Bragg gratings

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