System of polarization correlometry of polycrystalline layers of urine in the differentiation stage of diabetes

Yu. O. Ushenko; N. V. Pashkovskaya; Y. F. Marchuk; O. V. Dubolazov; V. O. Savich

doi:10.1117/12.2187793

26 August 2015 System of polarization correlometry of polycrystalline layers of urine in the differentiation stage of diabetes

Yu. O. Ushenko, N. V. Pashkovskaya, Y. F. Marchuk, O. V. Dubolazov, V. O. Savich

Author Affiliations +

Proceedings Volume 9584, Ultrafast Nonlinear Imaging and Spectroscopy III; 958414 (2015) https://doi.org/10.1117/12.2187793
Event: SPIE Optical Engineering + Applications, 2015, San Diego, California, United States

Abstract

The work consists of investigation results of diagnostic efficiency of a new azimuthally stable Muellermatrix method of analysis of laser autofluorescence coordinate distributions of biological liquid layers. A new model of generalized optical anisotropy of biological tissues protein networks is proposed in order to define the processes of laser autofluorescence. The influence of complex mechanisms of both phase anisotropy (linear birefringence and optical activity) and linear (circular) dichroism is taken into account. The interconnections between the azimuthally stable Mueller-matrix elements characterizing laser autofluorescence and different mechanisms of optical anisotropy are determined. The statistic analysis of coordinate distributions of such Mueller-matrix rotation invariants is proposed. Thereupon the quantitative criteria (statistic moments of the 1st to the 4th order) of differentiation of human urine polycrystalline layers for the sake of diagnosing and differentiating cholelithiasis with underlying chronic cholecystitis (group 1) and diabetes mellitus of degree II (group 2) are estimated.

Citation Download Citation

Yu. O. Ushenko, N. V. Pashkovskaya, Y. F. Marchuk, O. V. Dubolazov, and V. O. Savich "System of polarization correlometry of polycrystalline layers of urine in the differentiation stage of diabetes", Proc. SPIE 9584, Ultrafast Nonlinear Imaging and Spectroscopy III, 958414 (26 August 2015); https://doi.org/10.1117/12.2187793

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