Paper
9 March 2015 Combination therapy of potential gene to enhance oral cancer therapeutic effect
Author Affiliations +
Proceedings Volume 9324, Biophotonics and Immune Responses X; 932417 (2015) https://doi.org/10.1117/12.2081129
Event: SPIE BiOS, 2015, San Francisco, California, United States
Abstract
The epidermal growth factor receptor (EGFR) over-regulation related to uncontrolled cell division and promotes progression in tumor. Over-expression of human epidermal growth factor receptor (EGFR) has been detected in oral cancer cells. EGFR-targeting agents are potential therapeutic modalities for treating oral cancer based on our in vitro study. Liposome nanotechnology is used to encapsulate siRNA and were modified with target ligand to receptors on the surface of tumor cells. We used EGFR siRNA to treat oral cancer in vitro.
© (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chia-Hsien Yeh and Yih-Chih Hsu "Combination therapy of potential gene to enhance oral cancer therapeutic effect", Proc. SPIE 9324, Biophotonics and Immune Responses X, 932417 (9 March 2015); https://doi.org/10.1117/12.2081129
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KEYWORDS
Cancer

Receptors

Tumors

In vitro testing

Nanoparticles

Nanotechnology

Photodynamic therapy

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