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13 March 2014 Front Matter: Volume 8946
Abstract
This PDF file contains the front matter associated with SPIE Proceedings Volume 8946, including the Title Page, Copyright Information, Table of Contents, and the Conference Committee listing.

The papers included in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee. Some conference presentations may not be available for publication. The papers published in these proceedings reflect the work and thoughts of the authors and are published herein as submitted. The publisher is not responsible for the validity of the information or for any outcomes resulting from reliance thereon.

Please use the following format to cite material from this book:

Author(s), “Title of Paper,” in Optical Elastography and Tissue Biomechanics, edited by Kirill V. Larin, David D. Sampson, Proceedings of SPIE Vol. 8946 (SPIE, Bellingham, WA, 2014) Article CID Number.

ISSN: 1605-7422

ISBN: 9780819498595

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Conference Committee

Symposium Chairs

  • James G. Fujimoto, Massachusetts Institute of Technology (United States)

  • R. Rox Anderson, Wellman Center for Photomedicine, Massachusetts General Hospital (United States) and Harvard School of Medicine (United States)

Program Track Chairs

  • Steven L. Jacques, Oregon Health & Science University (United States)

  • William P. Roach, U.S. Air Force (United States)

Conference Chairs

  • Kirill V. Larin, University of Houston (United States)

  • David D. Sampson, The University of Western Australia (Australia)

Conference Program Committee

  • Jeffrey C. Bamber, Institute of Cancer Research (United Kingdom)

  • A. Claude Boccara, Institut Langevin (France)

  • Stephen A. Boppart M.D., University of Illinois at Urbana-Champaign (United States)

  • Brett E. Bouma, Wellman Center for Photomedicine (United States)

  • Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)

  • Donald D. Duncan, Portland State University (United States)

  • Kishan Dholakia, University of St. Andrews (United Kingdom)

  • Daniel S. Elson, Imperial College London (United Kingdom)

  • Mathias Fink, Institut Langevin (France)

  • Brendan F. Kennedy, The University of Western Australia (Australia)

  • Sean J. Kirkpatrick, Michigan Technological University (United States)

  • Seemantini K. Nadkarni, Harvard Medical School (United States)

  • Kentaro Nakamura, Tokyo Institute of Technology (Japan)

  • Amy L. Oldenburg, The University of North Carolina at Chapel Hill (United States)

  • Francesco S. Pavone, European Laboratory for Non-linear Spectroscopy (Italy)

  • Giuliano Scarcelli, Harvard Medical School (United States)

  • Gijs van Soest, Erasmus MC (Netherlands)

  • Victor X. D. Yang, Ryerson University (Canada)

  • Seok Hyun A. Yun, Wellman Center for Photomedicine (United States)

  • Ruikang K. Wang, University of Washington (United States)

Session Chairs

  • 1 Optical Coherence Elastography I: Tissue Mechanical Contrast

    Kirill V. Larin, University of Houston (United States)

    David D. Sampson, The University of Western Australia (Australia)

  • 2 Optical Coherence Elastography II: Novel Methods

    Stephen A. Boppart M.D., University of Illinois at Urbana-Champaign (United States)

    Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)

  • 3 Ocular Biomechanics

    Giuliano Scarcelli, Harvard Medical School (United States)

    Ruikang K. Wang, University of Washington (United States)

  • 4 Elastography Methods and Applications

    Daniel S. Elson, Imperial College London (United Kingdom)

    A. Claude Boccara, Institut Langevin (France)

  • 5 Sub-Cellular and Membrane Biomechanics

    Francesco S. Pavone, European Laboratory for Non-linear Spectroscopy (Italy)

    Seok Hyun A. Yun, Wellman Center for Photomedicine (United States)

  • 6 Optical Coherence Elastography III: Ultrasonic Loading

    Victor X. D. Yang, Ryerson University (Canada)

    Brendan F. Kennedy, The University of Western Australia (Australia)

  • 7 Cellular Biomechanics and Applications

    Amy L. Oldenburg, The University of North Carolina at Chapel Hill (United States)

    Seemantini K. Nadkarni, Harvard Medical School (United States)

Introduction

Optical elastography is the use of optics to characterize cells and tissues based on their elastic and viscoelastic mechanical properties. In utilizing the high-resolution capability of optics, this rapidly emerging field builds on and complements the related fields of ultrasound and MR elastography, as well as existing methods for biomechanics, such as atomic force microscopy and rheology.

Mechanical forces play an important role in the behavior and development of cells at all spatial scales, from cells and their constituents, to tissues and organs. Such forces profoundly influence the health, structural integrity, and normal function of cells and organs. Accurate determination of cell and tissue biomechanical properties (e.g., Young’s or shear modulus) is a vitally important area. High-resolution optical methods could help further the understanding of mechanical interactions, and mechanical properties, with application to clinical diagnosis and interpretation of a wide range of diseases.

The inaugural subconference was very vibrant and displayed a strongly multidisciplinary character bringing together technology and application experts in bioengineering, biophysics, cell biology, clinical sciences, medical imaging, optics and photonics, and tissue engineering. More than 35 contributed papers were built around two days of invited and contributed talks. Exceptional invited talks headlined the contributed program:

  • Stephen A. Boppart M.D., University of Illinois at Urbana-Champaign (United States) Optical coherence elastography techniques for assessing biomechanical properties of tissues and cells

  • Susana Marcos, Consejo Superior de Investigaciones Científicas (Spain) Corneal biomechanical properties from air-puff corneal deformation imaging

  • Kishan Dholakia, University of St. Andrews (United Kingdom) New light on cell manipulation and rheology

  • Ruikang K. Wang, University of Washington (United States) Use of phase sensitive OCT to track and visualize dynamic mechanical wave propagation within tissue

Many topics were covered and highlights include the impressive advances in optical coherence elastography techniques, particularly in compression methods and shear wave visualization. Applications in the anterior eye proved popular, with some interest also in breast cancer. Optical elastography and tissue biomechanics confirmed its status as a rapidly emerging area—we look forward with excitement and anticipation to see what the next twelve months will bring. In the meantime, please enjoy reading the papers submitted for this volume.

Kirill V. Larin

David D. Sampson

© (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
"Front Matter: Volume 8946", Proc. SPIE 8946, Optical Elastography and Tissue Biomechanics, 894601 (13 March 2014); https://doi.org/10.1117/12.2052752
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KEYWORDS
Tissue optics

Elastography

Biomedical optics

Coherence (optics)

Nonlinear optics

Optical coherence tomography

Spectroscopy

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