AC field induced cell membrane temperature gradients

Allen L. Garner; Maxim Deminsky; V. Bogdan Neculaes; Boris Potapkin

doi:10.1117/12.2045051

13 March 2014 AC field induced cell membrane temperature gradients

Allen L. Garner, Maxim Deminsky, V. Bogdan Neculaes, Boris Potapkin

Proceedings Volume 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications; 89411Q (2014) https://doi.org/10.1117/12.2045051
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

While generally inducing minimal heating in many biomedical applications, electric fields may still induce significant temperature gradients, particularly for pulses of short duration and AC (sinusoidal) fields of high frequency, such as microwaves. This paper extends a recent analysis of temperature gradients across a biological cell and membrane for single pulses [(A. L. Garner, et al., J. Appl. Phys. 113, 214701 (2013).] to multiple pulses or AC fields where the time between the two pulses, or the period for AC signals, is shorter than the thermal diffusion time. We calculate profiles of the induced temperature changes and gradients across a biological cell for AC wave of different frequencies and show that the location of the peak temperature and gradient shifts toward the center of the cell during subsequent half-waves. Higher frequency fields induce higher temperature gradients with the temperature gradient shifts toward the center of the cell for subsequent cycles.

Citation Download Citation

Allen L. Garner, Maxim Deminsky, V. Bogdan Neculaes, and Boris Potapkin "AC field induced cell membrane temperature gradients", Proc. SPIE 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications, 89411Q (13 March 2014); https://doi.org/10.1117/12.2045051

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
9 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Temperature metrology

Diffusion

Microwave radiation

Solids

Biomedical optics

Biological research

Chemical elements

Show All Keywords

Keywords/Phrases

Search In:

Publication Years