Predictive analysis of optical ablation in several dermatological tumoral tissues

F. Fanjul-Vélez; A. Blanco-Gutiérrez; I. Salas-García; N. Ortega-Quijano; J. L. Arce-Diego

doi:10.1117/12.2031948

24 June 2013 Predictive analysis of optical ablation in several dermatological tumoral tissues

F. Fanjul-Vélez, A. Blanco-Gutiérrez, I. Salas-García, N. Ortega-Quijano, J. L. Arce-Diego

Proceedings Volume 8803, Medical Laser Applications and Laser-Tissue Interactions VI; 88030R (2013) https://doi.org/10.1117/12.2031948
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

Optical techniques for treatment and characterization of biological tissues are revolutionizing several branches of medical praxis, for example in ophthalmology or dermatology. The non-invasive, non-contact and non-ionizing character of optical radiation makes it specially suitable for these applications. Optical radiation can be employed in medical ablation applications, either for tissue resection or surgery. Optical ablation may provide a controlled and clean cut on a biological tissue. This is particularly relevant in tumoral tissue resection, where a small amount of cancerous cells could make the tumor appear again. A very important aspect of tissue optical ablation is then the estimation of the affected volume. In this work we propose a complete predictive model of tissue ablation that provides an estimation of the resected volume. The model is based on a Monte Carlo approach for the optical propagation of radiation inside the tissue, and a blow-off model for tissue ablation. This model is applied to several types of dermatological tumoral tissues, specifically squamous cells, basocellular and infiltrative carcinomas. The parameters of the optical source are varied and the estimated resected volume is calculated. The results for the different tumor types are presented and compared. This model can be used for surgical planning, in order to assure the complete resection of the tumoral tissue.

Citation Download Citation

F. Fanjul-Vélez, A. Blanco-Gutiérrez, I. Salas-García, N. Ortega-Quijano, and J. L. Arce-Diego "Predictive analysis of optical ablation in several dermatological tumoral tissues", Proc. SPIE 8803, Medical Laser Applications and Laser-Tissue Interactions VI, 88030R (24 June 2013); https://doi.org/10.1117/12.2031948

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available