New polarimetric investigations on human tissues using ultra-short laser imaging polarimetry

Iulian Ionita; Ovidiu Toma

doi:10.1117/12.916609

22 November 2011 New polarimetric investigations on human tissues using ultra-short laser imaging polarimetry

Iulian Ionita, Ovidiu Toma

Proceedings Volume 8338, Tenth International Conference on Correlation Optics; 83380B (2011) https://doi.org/10.1117/12.916609
Event: Correlation Optics 2011, 2011, Chernivsti, Ukraine

Abstract

We report in this paper some new polarimetric investigations made on pathologically modified human tissues, using the ultra-short laser imaging polarimetry. This technique can be applied for a wide variety of objects with polarization inhomogeneous structure. Real biological tissues have an optically inhomogeneous structure, so any changes produced in the optical polarization state of a light beam passing through such samples (or reflected by them) can reveal important information about the respective biological tissue. The influence of the geometrical architectonics of a cancerous liver tissue on the polarization properties of an ultra-short laser beam who passes through such a sample is radical and can be seen both in the transmitted polarized light, as well as in the SHG (second harmonic generation) polarized light. We used a polarization sensitive imaging system, whose basic optical scheme has been previously published, this time a modified version of the experimental set-up being used. The biological tissue investigated in this paper was a slide of liver tumor. The polarization sensitive intensities for the transmitted and SHG light were measured with two detectors for different polarimetric configurations of the set-up. Experiments show a significant difference between transmitted and, respectively, SHG light behavior.

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Iulian Ionita and Ovidiu Toma "New polarimetric investigations on human tissues using ultra-short laser imaging polarimetry", Proc. SPIE 8338, Tenth International Conference on Correlation Optics, 83380B (22 November 2011); https://doi.org/10.1117/12.916609

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KEYWORDS

Second-harmonic generation

Tissues

Polarization

Collagen

Polarimetry

Liver

Laser imaging

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