Optical property change of blood on an optical window boundary by 660-nm band laser irradiation

Mei Takahashi; Arisa Ito; Tsunenori Arai

doi:10.1117/12.905845

9 February 2012 Optical property change of blood on an optical window boundary by 660-nm band laser irradiation

Mei Takahashi, Arisa Ito, Tsunenori Arai

Author Affiliations +

Proceedings Volume 8221, Optical Interactions with Tissue and Cells XXIII; 822116 (2012) https://doi.org/10.1117/12.905845
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

We studied an optical interaction on an optical window and blood boundary during the CW laser irradiation in 660 nm band until blood charring occurrence. We previously reported that a pre-charring optical behavior may be detected by diffuse-reflected-light power time-history. The aim of this study is to measure absorption coefficient (μa) and reduced scattering coefficient (μ's) of a blood model to explain this pre-charring optical behavior. The blood model sandwiched between 2 glass slides to simulate the interface between blood and the optical window was used. A double integrating sphere system was constructed. The red laser in 660 nm band was irradiated to the sandwiched blood model. Fourty W/cm² in irradiance was used as the maximum irradiance during irradiation via the laser catheter in vivo. μa and μ's in the irradiated laser wavelength were measured continuously until blood charring occurrence using inverse adding doubling analysis. Continuous μa increase of 5-10% from the initial value until charring was observed. Decrease of μ's with 8-10% during 15-30 s before charring following broad peak was obtained. We think these μa and μ's changes may explain the pre-charring optical behavior detected by the diffuse-reflected-light power time-history in our reported study.

Citation Download Citation

Mei Takahashi, Arisa Ito, and Tsunenori Arai "Optical property change of blood on an optical window boundary by 660-nm band laser irradiation", Proc. SPIE 8221, Optical Interactions with Tissue and Cells XXIII, 822116 (9 February 2012); https://doi.org/10.1117/12.905845

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