Extracting scattering coefficient and anisotropy factor of tissue using optical coherence tomography

Niloy Choudhury; Steven L. Jacques

doi:10.1117/12.907401

9 February 2012 Extracting scattering coefficient and anisotropy factor of tissue using optical coherence tomography

Niloy Choudhury, Steven L. Jacques

Proceedings Volume 8221, Optical Interactions with Tissue and Cells XXIII; 822111 (2012) https://doi.org/10.1117/12.907401
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Determination of tissue optical properties is important as it will lead to better design of optical diagnostic tools, improvement in laser therapy, photo dynamic therapy dosimetry, drug pharmacokinetics, etc. We have developed a theoretical model for OCT signal using Monte Carlo simulation that allows us to fit values extracted from the OCT signal, namely, reflectance, ρ, and the total optical attenuation coefficient, μt, to obtain optical properties of tissue (scattering coefficient, μs, and anisotropy factor, g). Using this method we have extracted optical properties of different tissue types, e.g., skin, muscle, liver, and brain of mouse.

Citation Download Citation

Niloy Choudhury and Steven L. Jacques "Extracting scattering coefficient and anisotropy factor of tissue using optical coherence tomography", Proc. SPIE 8221, Optical Interactions with Tissue and Cells XXIII, 822111 (9 February 2012); https://doi.org/10.1117/12.907401

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