Screening prostate cancer using a portable near infrared scanning imaging unit with an optical fiber-based rectal probe

Yang Pu; Wubao Wang; Guichen Tang; Yury Budansky; Mikhail Sharonov; Min Xu; Samuel Achilefu; James A. Eastham; Robert R. Alfano

doi:10.1117/12.904254

31 January 2012 Screening prostate cancer using a portable near infrared scanning imaging unit with an optical fiber-based rectal probe

Yang Pu, Wubao Wang, Guichen Tang, Yury Budansky, Mikhail Sharonov, Min Xu, Samuel Achilefu, James A. Eastham, Robert R. Alfano

Author Affiliations +

Proceedings Volume 8220, Optical Biopsy X; 822002 (2012) https://doi.org/10.1117/12.904254
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

A portable near infrared scanning polarization imaging unit with an optical fiber-based rectal probe, namely Photonic Finger, was designed and developed o locate the 3D position of abnormal prostate site inside normal prostate tissue. An inverse algorithm, Optical Tomography using Independent Component Analysis (OPTICA) was improved particularly to unmix the signal from targets (cancerous tissue) embedded in a turbid medium (normal tissue) in the backscattering imaging geometry. Photonic Finger combined with OPTICA was tested to characterize different target(s) inside different tissue medium, including cancerous prostate tissue embedded by large piece of normal tissue.

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Yang Pu, Wubao Wang, Guichen Tang, Yury Budansky, Mikhail Sharonov, Min Xu, Samuel Achilefu, James A. Eastham, and Robert R. Alfano "Screening prostate cancer using a portable near infrared scanning imaging unit with an optical fiber-based rectal probe", Proc. SPIE 8220, Optical Biopsy X, 822002 (31 January 2012); https://doi.org/10.1117/12.904254

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