EPR study of the effect of terahertz radiation on the albumin conformation dynamics

Eugenia F. Nemova; Olga P. Cherkasova; Vyacheslav I. Fedorov

doi:10.1117/12.880903

11 January 2011 EPR study of the effect of terahertz radiation on the albumin conformation dynamics

Eugenia F. Nemova, Olga P. Cherkasova, Vyacheslav I. Fedorov

Proceedings Volume 7993, ICONO 2010: International Conference on Coherent and Nonlinear Optics; 799325 (2011) https://doi.org/10.1117/12.880903
Event: International Conference on Coherent and Nonlinear Optics (ICONO 2010) and International Conference on Lasers, Applications and Technologies (LAT 2010), 2010, Kazan, Russian Federation

Abstract

Effect of the preliminary irradiation of bovine serum albumin (BSA) in the terahertz spectral range on the conformation changes revealed with the help of EPR spectroscopy was investigated using the spin probing technique. The formation of the spin probe occurs directly in the aqueous solution of BSA from a nitrone compound (dihydropyrazine dioxide). It was shown that irradiation causes changes in the parameters of the EPR spectrum of the spin probe. An approach to linking the observed changes with the structural characteristics of reaction centres - the functional groups of amino acids comprising BSA - was outlined.

Citation Download Citation

Eugenia F. Nemova, Olga P. Cherkasova, and Vyacheslav I. Fedorov "EPR study of the effect of terahertz radiation on the albumin conformation dynamics", Proc. SPIE 7993, ICONO 2010: International Conference on Coherent and Nonlinear Optics, 799325 (11 January 2011); https://doi.org/10.1117/12.880903

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