Simultaneous image segmentation and medial structure estimation: application to 2D and 3D vessel tree extraction

Sherif Makram-Ebeid; Jean Stawiaski; Guillaume Pizaine

doi:10.1117/12.878126

14 March 2011 Simultaneous image segmentation and medial structure estimation: application to 2D and 3D vessel tree extraction

Sherif Makram-Ebeid, Jean Stawiaski, Guillaume Pizaine

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Proceedings Volume 7962, Medical Imaging 2011: Image Processing; 79623D (2011) https://doi.org/10.1117/12.878126
Event: SPIE Medical Imaging, 2011, Lake Buena Vista (Orlando), Florida, United States

Abstract

We propose a variational approach which combines automatic segmentation and medial structure extraction in a single computationally efficient algorithm. In this paper, we apply our approach to the analysis of vessels in 2D X-ray angiography and 3D X-ray rotational angiography of the brain. Other variational methods proposed in the literature encode the medial structure of vessel trees as a skeleton with associated vessel radii. In contrast, our method provides a dense smooth level set map which sign provides the segmentation. The ridges of this map define the segmented regions skeleton. The differential structure of the smooth map (in particular the Hessian) allows the discrimination between tubular and other structures. In 3D, both circular and non-circular tubular cross-sections and tubular branching can be handled conveniently. This algorithm allows accurate segmentation of complex vessel structures. It also provides key tools for extracting anatomically labeled vessel tree graphs and for dealing with challenging issues like kissing vessel discrimination and separation of entangled 3D vessel trees.

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Sherif Makram-Ebeid, Jean Stawiaski, and Guillaume Pizaine "Simultaneous image segmentation and medial structure estimation: application to 2D and 3D vessel tree extraction", Proc. SPIE 7962, Medical Imaging 2011: Image Processing, 79623D (14 March 2011); https://doi.org/10.1117/12.878126

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KEYWORDS

Image segmentation

Angiography

X-rays

Finite element methods

3D image processing

X-ray imaging

Brain

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