Demonstration of a reusable plasmonic polymer microarray sensing platform

Philip J. R. Roche; Maurice C. Cheung; Songzhe Wang; Behnam Banan; Vamsy P. Chodavarapu; Andrew G. Kirk

doi:10.1117/12.878848

11 February 2011 Demonstration of a reusable plasmonic polymer microarray sensing platform

Philip J. R. Roche, Maurice C. Cheung, Songzhe Wang, Behnam Banan, Vamsy P. Chodavarapu, Andrew G. Kirk

Proceedings Volume 7908, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VIII; 79080P (2011) https://doi.org/10.1117/12.878848
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

High throughput plasmonic sensors are a popular research field, standard surface plasmon resonance (SPR) instruments can achieve high throughput only in imaging configuration. This leads to consideration of pattern substrates and isolated nanoparticle arrays, both of which have some disadvantages. Spot functionalisation relies upon mask or pin printing to accomplish density, and this increase the complexity of use and standard operating procedures. Both patterned and nanoparticle arrays assay platforms are also commonly single use, unlike some SPR imaging and multi channel angular sensing SPR approaches. The microarray format proposed here is intended for multiple usages and regenerated, with a simple optical readout method. A plasmonic polymer of exquisite refractive index sensitivity and incorporate glass-like physical and mechanical stability provides the sensing element to the platform. Further, the standard sol-gel chemistry is well understood and amenable to easy covalent functionalisation as well as matrix methods such as nitrocellulose for biomolecule fictionalization. Two forms of polymer templating have been developed. For spots greater than 700μm a double side tape method can be applied and for sub 700μm patterned SU-8 and 100nm Aluminum reflective layer allow greater spot resolution. Proof of concept through refractive index sensing is demonstrated.

Citation Download Citation

Philip J. R. Roche, Maurice C. Cheung, Songzhe Wang, Behnam Banan, Vamsy P. Chodavarapu, and Andrew G. Kirk "Demonstration of a reusable plasmonic polymer microarray sensing platform", Proc. SPIE 7908, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VIII, 79080P (11 February 2011); https://doi.org/10.1117/12.878848

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available