Usefulness of texture features for segmentation of lungs with severe diffuse interstitial lung disease

Jiahui Wang; Feng Li; Qiang Li

doi:10.1117/12.844351

9 March 2010 Usefulness of texture features for segmentation of lungs with severe diffuse interstitial lung disease

Jiahui Wang, Feng Li, Qiang Li

Proceedings Volume 7624, Medical Imaging 2010: Computer-Aided Diagnosis; 76242W (2010) https://doi.org/10.1117/12.844351
Event: SPIE Medical Imaging, 2010, San Diego, California, United States

Abstract

We developed an automated method for the segmentation of lungs with severe diffuse interstitial lung disease (DILD) in multi-detector CT. In this study, we would like to compare the performance levels of this method and a thresholdingbased segmentation method for normal lungs, moderately abnormal lungs, severely abnormal lungs, and all lungs in our database. Our database includes 31 normal cases and 45 abnormal cases with severe DILD. The outlines of lungs were manually delineated by a medical physicist and confirmed by an experienced chest radiologist. These outlines were used as reference standards for the evaluation of the segmentation results. We first employed a thresholding technique for CT value to obtain initial lungs, which contain normal and mildly abnormal lung parenchyma. We then used texture-feature images derived from co-occurrence matrix to further segment lung regions with severe DILD. The segmented lung regions with severe DILD were combined with the initial lungs to generate the final segmentation results. We also identified and removed the airways to improve the accuracy of the segmentation results. We used three metrics, i.e., overlap, volume agreement, and mean absolute distance (MAD) between automatically segmented lung and reference lung to evaluate the performance of our segmentation method and the thresholding-based segmentation method. Our segmentation method achieved a mean overlap of 96.1%, a mean volume agreement of 98.1%, and a mean MAD of 0.96 mm for the 45 abnormal cases. On the other hand the thresholding-based segmentation method achieved a mean overlap of 94.2%, a mean volume agreement of 95.8%, and a mean MAD of 1.51 mm for the 45 abnormal cases. Our new method obtained higher performance level than the thresholding-based segmentation method.

Citation Download Citation

Jiahui Wang, Feng Li, and Qiang Li "Usefulness of texture features for segmentation of lungs with severe diffuse interstitial lung disease", Proc. SPIE 7624, Medical Imaging 2010: Computer-Aided Diagnosis, 76242W (9 March 2010); https://doi.org/10.1117/12.844351

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