Near-infrared spectroscopy with spectroscopic technique with wide range of wavelength information detects tissue oxygenation level clearly

Hideo Eda; Hiromichi Aoki; Shigeru Eura; Kazutoshi Ebe

doi:10.1117/12.842372

23 February 2010 Near-infrared spectroscopy with Spectroscopic technique with wide range of wavelength information detects tissue oxygenation level clearly

Hideo Eda, Hiromichi Aoki, Shigeru Eura, Kazutoshi Ebe

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Proceedings Volume 7557, Multimodal Biomedical Imaging V; 75570K (2010) https://doi.org/10.1117/12.842372
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Near-infrared spectroscopy (NIRS) is based on the modified-Lambert-Beer's law that changes in absorbance are proportional to changes in hemoglobin parameters. Majority of the conventional measurement methods uses only two or three wavelengths. In this research, basic examination of NIRS measurement was approached by acquiring wide range of wavelength information. Arterial occlusion task was performed by using the blood pressure cuff around the upper arm. Pressure of 200mmHg was then applied for about 3 minutes. During the arterial occlusion, the spectrum of the lower arm muscles was measured every 15 seconds, within the range of 600 to 1100nm. The secondary derivative spectrum was calculated from the measured spectrum. Arterial occlusion is a task which changes the oxygenation level of the tissue. The change can be regarded as the change of the spectrum form, not as the change of the baseline. Furthermore, it was found that other wavelength bands hold information correlating to this arterial occlusion task.

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Hideo Eda, Hiromichi Aoki, Shigeru Eura, and Kazutoshi Ebe "Near-infrared spectroscopy with Spectroscopic technique with wide range of wavelength information detects tissue oxygenation level clearly", Proc. SPIE 7557, Multimodal Biomedical Imaging V, 75570K (23 February 2010); https://doi.org/10.1117/12.842372

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KEYWORDS

Near infrared spectroscopy

Absorbance

Spectroscopy

Photonics

Tissue optics

Tissues

Absorption

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