Paper
2 March 2010 Measurement of the tear film and anterior chamber by confocal microscopy
Kim K. Buttenschön, John M. Girkin, Clive G. Wilson, Daniel J. Daly
Author Affiliations +
Proceedings Volume 7550, Ophthalmic Technologies XX; 755028 (2010) https://doi.org/10.1117/12.842187
Event: SPIE BiOS, 2010, San Francisco, California, United States
Abstract
We report on the development of a novel, low cost instrument that is capable of accurately measuring small, short and long term changes in the thickness of the cornea and tear film at high speed. The performance of the instrument was tested by measuring the influence of Allergan's OPTIVETM lubricating eye drops on the thickness of the cornea and tear film. Comparative measurements to quantify the performance were taken using Haag-Streit's LenStar. It was found that the newly developed instrument accurately measured a change in thickness of around 9 μm with an accuracy comparable to the LenStar, and with a standard deviation of less than 1 micrometer. Since the new instrument was not configured to resolve the tear film from the cornea, we are not yet able to distinguish the cause of the thickening.
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Kim K. Buttenschön, John M. Girkin, Clive G. Wilson, and Daniel J. Daly "Measurement of the tear film and anterior chamber by confocal microscopy", Proc. SPIE 7550, Ophthalmic Technologies XX, 755028 (2 March 2010); https://doi.org/10.1117/12.842187
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KEYWORDS
Eye

Cornea

Confocal microscopy

Beam splitters

Reflection

Polarization

Sensors

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