Oxygen saturation imaging of human retinal vessels and measurement in eye disease patient for clinical application

D. Nakamura; N. Matsuoka; K. Tatsuguchi; M. Ogata; Y. Yoshinaga; H. Enaida; T. Okada; T. Ishibashi

doi:10.1117/12.841434

2 March 2010 Oxygen saturation imaging of human retinal vessels and measurement in eye disease patient for clinical application

D. Nakamura, N. Matsuoka, K. Tatsuguchi, M. Ogata, Y. Yoshinaga, H. Enaida, T. Okada, T. Ishibashi

Author Affiliations +

Proceedings Volume 7550, Ophthalmic Technologies XX; 75501X (2010) https://doi.org/10.1117/12.841434
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

We have proposed a new automatic visualization procedure based the ratio of optical densities (ODs) obtained at two different wavelength for the oxygen saturation imaging in human retinal vessels. This method utilized the morphological processing and the line convergence index filter to estimate the reflection image of outside vessels and extract the vessel structure from retinal image, respectively. In the experimental measurement, clear difference between retinal arteries and veins has been observed. In this study, the data processing technique of the line convergence index filter was applied to a color fundus image to investigate the ability of vessel extraction. In addition, four-wavelength imaging was proposed to evaluate oxygen saturation of the retinal capillary vessels and to decrease the influence of the melanin pigmentation.

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D. Nakamura, N. Matsuoka, K. Tatsuguchi, M. Ogata, Y. Yoshinaga, H. Enaida, T. Okada, and T. Ishibashi "Oxygen saturation imaging of human retinal vessels and measurement in eye disease patient for clinical application", Proc. SPIE 7550, Ophthalmic Technologies XX, 75501X (2 March 2010); https://doi.org/10.1117/12.841434

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