High-performance intraoperative cone-beam CT on a mobile C-arm: an integrated system for guidance of head and neck surgery

J. H. Siewerdsen; M. J. Daly; H. Chan; S. Nithiananthan; N. Hamming; K. K. Brock; J. C. Irish

doi:10.1117/12.813747

13 March 2009 High-performance intraoperative cone-beam CT on a mobile C-arm: an integrated system for guidance of head and neck surgery

J. H. Siewerdsen, M. J. Daly, H. Chan, S. Nithiananthan, N. Hamming, K. K. Brock, J. C. Irish

Author Affiliations +

Proceedings Volume 7261, Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling; 72610J (2009) https://doi.org/10.1117/12.813747
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

A system for intraoperative cone-beam CT (CBCT) surgical guidance is under development and translation to trials in head and neck surgery. The system provides 3D image updates on demand with sub-millimeter spatial resolution and soft-tissue visibility at low radiation dose, thus overcoming conventional limitations associated with preoperative imaging alone. A prototype mobile C-arm provides the imaging platform, which has been integrated with several novel subsystems for streamlined implementation in the OR, including: real-time tracking of surgical instruments and endoscopy (with automatic registration of image and world reference frames); fast 3D deformable image registration (a newly developed multi-scale Demons algorithm); 3D planning and definition of target and normal structures; and registration / visualization of intraoperative CBCT with the surgical plan, preoperative images, and endoscopic video. Quantitative evaluation of surgical performance demonstrates a significant advantage in achieving complete tumor excision in challenging sinus and skull base ablation tasks. The ability to visualize the surgical plan in the context of intraoperative image data delineating residual tumor and neighboring critical structures presents a significant advantage to surgical performance and evaluation of the surgical product. The system has been translated to a prospective trial involving 12 patients undergoing head and neck surgery - the first implementation of the research prototype in the clinical setting. The trial demonstrates the value of high-performance intraoperative 3D imaging and provides a valuable basis for human factors analysis and workflow studies that will greatly augment streamlined implementation of such systems in complex OR environments.

Citation Download Citation

J. H. Siewerdsen, M. J. Daly, H. Chan, S. Nithiananthan, N. Hamming, K. K. Brock, and J. C. Irish "High-performance intraoperative cone-beam CT on a mobile C-arm: an integrated system for guidance of head and neck surgery", Proc. SPIE 7261, Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling, 72610J (13 March 2009); https://doi.org/10.1117/12.813747

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