Visualizing conserved gene location across microbe genomes

Chris D. Shaw

doi:10.1117/12.811912

20 January 2009 Visualizing conserved gene location across microbe genomes

Chris D. Shaw

Proceedings Volume 7243, Visualization and Data Analysis 2009; 724306 (2009) https://doi.org/10.1117/12.811912
Event: IS&T/SPIE Electronic Imaging, 2009, San Jose, California, United States

Abstract

This paper introduces an analysis-based zoomable visualization technique for displaying the location of genes across many related species of microbes. The purpose of this visualizatiuon is to enable a biologist to examine the layout of genes in the organism of interest with respect to the gene organization of related organisms. During the genomic annotation process, the ability to observe gene organization in common with previously annotated genomes can help a biologist better confirm the structure and function of newly analyzed microbe DNA sequences. We have developed a visualization and analysis tool that enables the biologist to observe and examine gene organization among genomes, in the context of the primary sequence of interest. This paper describes the visualization and analysis steps, and presents a case study using a number of Rickettsia genomes.

Citation Download Citation

Chris D. Shaw "Visualizing conserved gene location across microbe genomes", Proc. SPIE 7243, Visualization and Data Analysis 2009, 724306 (20 January 2009); https://doi.org/10.1117/12.811912

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