Optoacoustic detection of thermal lesions

Michel G. Arsenault; Michael C. Kolios; William M. Whelan

doi:10.1117/12.810913

24 February 2009 Optoacoustic detection of thermal lesions

Michel G. Arsenault, Michael C. Kolios, William M. Whelan

Proceedings Volume 7177, Photons Plus Ultrasound: Imaging and Sensing 2009; 71771V (2009) https://doi.org/10.1117/12.810913
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Minimally invasive thermal therapy is being investigated as an alternative cancer treatment. It involves heating tissues to greater than 55°C over a period of a few minutes, which results in tissue coagulation. Optoacoustic (OA) imaging is a new imaging technique that involves exposing tissues to pulsed light and detecting the acoustic waves that are generated. In this study, adult bovine liver tissue samples were heated using continuous wave laser energy for various times, then scanned using an optoacoustic imaging system. Large optoacoustic signal variability was observed in the native tissue prior to heating. OA signal amplitude increased with maximum tissue temperature achieved, characterized by a correlation coefficient of 0.63. In this study we show that there are detectable changes in optoacoustic signal strength that arise from tissue coagulation, which demonstrates the potential of optoacoustic technology for the monitoring of thermal therapy delivery.

Citation Download Citation

Michel G. Arsenault, Michael C. Kolios, and William M. Whelan "Optoacoustic detection of thermal lesions", Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71771V (24 February 2009); https://doi.org/10.1117/12.810913

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available