Design of a handheld optical coherence microscopy endoscope

Vrushali R. Korde; Erica Liebmann; Jennifer K. Barton

doi:10.1117/12.809896

2 March 2009 Design of a handheld optical coherence microscopy endoscope

Vrushali R. Korde, Erica Liebmann, Jennifer K. Barton

Proceedings Volume 7172, Endoscopic Microscopy IV; 71720D (2009) https://doi.org/10.1117/12.809896
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Optical Coherence Microscopy (OCM) combines coherence gating, high numerical aperture optics, and a fiber core pinhole to provide high axial and lateral resolution with relatively large depth of imaging. We present a handheld rigid OCM endoscope with a 6 mm diameter tip, 1 mm scan width, and 1 mm imaging depth. This probe will allow noninvasive imaging of fine structural detail in vivo. X-Y scanning is performed distally with mirrors mounted to micro galvonometer scanners incorporated into the endoscope handle. Two scanning doublet lenses relay the stop from the galvonometers to the afocal relay stop. The endoscope optical design consists of an afocal Hopkins relay lens system and a 0.4 NA objective. To allow focusing at various depths in the tissue, the endoscope housing is designed in two pieces screwed together with a fine pitch threads. A small rotation of the outer housing moves the lenses proximal and distal relative to the window, causing the focal location in the tissue to change. The space between the final objective lens and the window is filled with distilled water to avoid misalignment of the focus and coherence gate. A knife edge test was performed and the line spread function FWHM was measured to be 2.25 μm. The MTF has at least 0.3 contrast at a 5 μm line pair. This rigid handheld OCM endoscope will be useful for application ranging from minimally invasive surgical imaging to assessing dysplasia and sun damage in skin.

Citation Download Citation

Vrushali R. Korde, Erica Liebmann, and Jennifer K. Barton "Design of a handheld optical coherence microscopy endoscope", Proc. SPIE 7172, Endoscopic Microscopy IV, 71720D (2 March 2009); https://doi.org/10.1117/12.809896

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