Three-dimensional retinal blood flow analysis using joint spectral and time domain optical coherence tomography

Anna Szkulmowska; Maciej Szkulmowski; Daniel Szlag; Danuta Bukowska; Szymon Tamborski; Andrzej Kowalczyk; Maciej Wojtkowski

doi:10.1117/12.808200

18 February 2009 Three-dimensional retinal blood flow analysis using joint spectral and time domain optical coherence tomography

Anna Szkulmowska, Maciej Szkulmowski, Daniel Szlag, Danuta Bukowska, Szymon Tamborski, Andrzej Kowalczyk, Maciej Wojtkowski

Author Affiliations +

Proceedings Volume 7163, Ophthalmic Technologies XIX; 71630Q (2009) https://doi.org/10.1117/12.808200
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

In this submission we demonstrate a new application of the joint Spectral and Time domain Optical Coherence Tomography (STdOCT) technique for segmenting and measuring the retinal blood flow velocity in three dimensions. The method is based on direct detection of Doppler shift that arises in time during the measurement. New scanning protocols and analysis tools are proposed to create velocity distribution maps of the retina and to segment and visualize 3D vasculature of human eye in-vivo. STdOCT segmentation is more sensitive than methods based on phase measurements and calculations are more straightforward than other techniques, which require more complex experimental setup and more sophisticated numerical tools. The usage of ultra-fast line scan camera allows to broaden the axial velocity range up to ±24mm/s, thus all high flows in human retina can be registered.

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Anna Szkulmowska, Maciej Szkulmowski, Daniel Szlag, Danuta Bukowska, Szymon Tamborski, Andrzej Kowalczyk, and Maciej Wojtkowski "Three-dimensional retinal blood flow analysis using joint spectral and time domain optical coherence tomography", Proc. SPIE 7163, Ophthalmic Technologies XIX, 71630Q (18 February 2009); https://doi.org/10.1117/12.808200

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