A low-cost linear DC - 35 MHz high-power LED driver for continuous wave (CW) and fluorescence lifetime imaging (FLIM)

Sylvain Gioux; Vida Kianzad; Razvan Ciocan; Hak Soo Choi; Chad Nelson; Jeffrey Thumm; Robert J. Filkins; Stephen J. Lomnes; John V. Frangioni

doi:10.1117/12.779196

8 February 2008 A low-cost linear DC - 35 MHz high-power LED driver for continuous wave (CW) and fluorescence lifetime imaging (FLIM)

Sylvain Gioux, Vida Kianzad, Razvan Ciocan, Hak Soo Choi, Chad Nelson, Jeffrey Thumm, Robert J. Filkins, Stephen J. Lomnes, John V. Frangioni

Author Affiliations +

Proceedings Volume 6848, Advanced Biomedical and Clinical Diagnostic Systems VI; 684807 (2008) https://doi.org/10.1117/12.779196
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Near-infrared (NIR) fluorescence has the potential to provide surgeons with real-time intraoperative image-guidance. Increasing the signal-to-background ratio of fluorescent agents involves delivering a controllable excitation fluence rate of proper wavelength and/or using complementary imaging techniques such as FLIM. In this study we describe a low-cost linear driver circuit capable of driving Light Emitting Diodes (LEDs) from DC to 35 MHz, at high power, and which permit fluorescence CW and lifetime measurements. The electronic circuit Gerber files described in this article and the list of components are available online at www.frangionilab.org.

Citation Download Citation

Sylvain Gioux, Vida Kianzad, Razvan Ciocan, Hak Soo Choi, Chad Nelson, Jeffrey Thumm, Robert J. Filkins, Stephen J. Lomnes, and John V. Frangioni "A low-cost linear DC - 35 MHz high-power LED driver for continuous wave (CW) and fluorescence lifetime imaging (FLIM)", Proc. SPIE 6848, Advanced Biomedical and Clinical Diagnostic Systems VI, 684807 (8 February 2008); https://doi.org/10.1117/12.779196

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