Novel fiber-optic probe design for depth-resolved fluorescence measurements: Monte Carlo simulations

Franck Jaillon; Wei Zheng; Zhiwei Huang

doi:10.1117/12.755262

19 November 2007 Novel fiber optic-probe design for depth-resolved fluorescence measurements: Monte Carlo simulations

Franck Jaillon, Wei Zheng, Zhiwei Huang

Proceedings Volume 6826, Optics in Health Care and Biomedical Optics III; 68261D (2007) https://doi.org/10.1117/12.755262
Event: Photonics Asia 2007, 2007, Beijing, China

Abstract

Fluorescence spectroscopy diagnostics on epithelium tissues requires being able to obtain depth resolved measurements. We study here an optical probe combining a ball lens, a flat tip excitation fiber and a bevel collection fiber. Varying the angle of the bevel collection fiber is seen to be a way of changing the depth of the fluorescence collected signal. Fixing the excitation-collection distance, we observe that large bevel angles of the collection fiber tip allows to augment the fluorescence collected signal of the stroma, whereas small angles improve the signal from the epithelial layer.

Citation Download Citation

Franck Jaillon, Wei Zheng, and Zhiwei Huang "Novel fiber optic-probe design for depth-resolved fluorescence measurements: Monte Carlo simulations", Proc. SPIE 6826, Optics in Health Care and Biomedical Optics III, 68261D (19 November 2007); https://doi.org/10.1117/12.755262

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