Ultrasound-only dosimetry for prostate brachytherapy: preliminary phantom results

Xu Wen; S. E. Salcudean; P. D. Lawrence; J. Morris

doi:10.1117/12.710241

12 March 2007 Ultrasound-only dosimetry for prostate brachytherapy: preliminary phantom results

Xu Wen, S. E. Salcudean, P. D. Lawrence, J. Morris

Proceedings Volume 6513, Medical Imaging 2007: Ultrasonic Imaging and Signal Processing; 65130M (2007) https://doi.org/10.1117/12.710241
Event: Medical Imaging, 2007, San Diego, CA, United States

Abstract

Accurate and fast seed localization plays a key role in computing dosimetry for prostate brachytherapy. Because transrectal ultrasound is the primary imaging modality providing the guidance for prostate brachytherapy, an ultrasound-only approach for dosimetry would offer many benefits. In this paper, we propose an ultrasound only dosimetry solution, in which the brachytherapy seeds are located in reflected power images computed from ultrasonic radio frequency signals and the boundary of the prostate is delineated from B-mode TRUS and vibroelastography images as the prostate is stiffer than the surrounding tissue. The location of the implanted seeds relative to the prostate boundary is thus obtained. As only one imaging modality, ultrasound, is used, image registration is easy to implement. A prostate phantom with seeds embedded within it was built to evaluate the proposed approach. To measure the seed localization accuracy in the reflected power images, the phantom was scanned by CT as well. Experimental results show that the implanted seeds can be successfully located in the reflected power images with high contrast and accuracy, and that the contour of the "prostate" can be detected in the ultrasound vibro-elastography images outside the shadow of the seeds.

Citation Download Citation

Xu Wen, S. E. Salcudean, P. D. Lawrence, and J. Morris "Ultrasound-only dosimetry for prostate brachytherapy: preliminary phantom results", Proc. SPIE 6513, Medical Imaging 2007: Ultrasonic Imaging and Signal Processing, 65130M (12 March 2007); https://doi.org/10.1117/12.710241

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available