Regularized reconstruction of dynamic gated cardiac SPECT images

Mingwu Jin; Yongyi Yang

doi:10.1117/12.714703

28 February 2007 Regularized reconstruction of dynamic gated cardiac SPECT images

Mingwu Jin, Yongyi Yang

Proceedings Volume 6498, Computational Imaging V; 649805 (2007) https://doi.org/10.1117/12.714703
Event: Electronic Imaging 2007, 2007, San Jose, CA, United States

Abstract

In this work we propose a spatio-temporal approach for reconstruction of dynamic gated cardiac SPECT images. As in traditional gated cardiac SPECT, the cardiac cycle is divided into a number of gate intervals, but the tracer distribution is treated as a time-varying signal for each gate. Our goal is to produce a dynamic image sequence that shows both cardiac motion and time-varying tracer distribution. To combat the ill-conditioned nature of the problem, we use B-spline basis functions to regulate the time activities curves, and apply a joint MAP estimation approach based on motion compensation for reconstruction of all the different gates. We also explore the benefit of using a time-varying regularization prior for the gated dynamic images. The proposed approach is evaluated using a dynamic version of the 4D gated mathematical cardiac torso phantom (gMCAT) simulating a gated SPECT perfusion acquisition with Technitium-99m labeled Teboroxime.

Citation Download Citation

Mingwu Jin and Yongyi Yang "Regularized reconstruction of dynamic gated cardiac SPECT images", Proc. SPIE 6498, Computational Imaging V, 649805 (28 February 2007); https://doi.org/10.1117/12.714703

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