Convergence analysis and preliminary experimental feasibility for MRI-localized region spectroscopy with NIR diffuse optical tomography

Jia Wang; Scott Davis; Shudong Jiang; Brian W. Pogue; Keith D. Paulsen

doi:10.1117/12.699371

27 March 2007 Convergence analysis and preliminary experimental feasibility for MRI-localized region spectroscopy with NIR diffuse optical tomography

Jia Wang, Scott Davis, Shudong Jiang, Brian W. Pogue, Keith D. Paulsen

Author Affiliations +

Proceedings Volume 6434, Optical Tomography and Spectroscopy of Tissue VII; 64341B (2007) https://doi.org/10.1117/12.699371
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

NIR tomography image reconstruction can be improved by incorporating spectral constraints and prior spatial information. The convergence of scattering power was studied based on the distribution of projection error with different parameters. The reason that scattering properties are harder to recover than chromophore concentrations was discussed. Using "hard prior" spectral reconstruction, the role of stopping criteria was found to be important. Multiple wavelength simulations were used to choose suitable stopping criteria. Preliminary tests using a wavelength tunable Ti-Sapphire laser shows promise for frequency domain measurements covering a wide range of wavelengths.

Citation Download Citation

Jia Wang, Scott Davis, Shudong Jiang, Brian W. Pogue, and Keith D. Paulsen "Convergence analysis and preliminary experimental feasibility for MRI-localized region spectroscopy with NIR diffuse optical tomography", Proc. SPIE 6434, Optical Tomography and Spectroscopy of Tissue VII, 64341B (27 March 2007); https://doi.org/10.1117/12.699371

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available