Combined confocal/en face optical coherence tomography imaging of the human eye fundus in vivo in the 1050 nm spectral region

Radu G. Cucu; John A. Rogers; Mark W. Hathaway; Justin Pedro; Adrian Gh. Podoleanu; Richard B. Rosen M.D.

doi:10.1117/12.704320

7 February 2007 Combined confocal/en face optical coherence tomography imaging of the human eye fundus in vivo in the 1050 nm spectral region

Radu G. Cucu, John A. Rogers, Mark W. Hathaway, Justin Pedro, Adrian Gh. Podoleanu, Richard B. Rosen M.D.

Author Affiliations +

Proceedings Volume 6429, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI; 642903 (2007) https://doi.org/10.1117/12.704320
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

The 1020-1080 nm spectral region appears as a viable alternative to the 700-900 nm spectral band for in vivo eye fundus OCT imaging due to a local absorption minimum of water (main constituent of the eye aqueous and vitreous). Light at these wavelengths also experiences less attenuation due to lower scattering and absorption by melanin in the retinal pigment epithelium and choroid, which results in deeper penetration of the probe beam in the choroid. T-scan based en face OCT is a modification of the OCT technique that has the unique capability of acquiring both longitudinal (B-scans) and tranversal (C-scans) OCT images of the eye fundus in real time and allows the addition of a confocal scanning ophthalmoscope channel to the OCT instrument. We report for the first time a combined T-scan based en face OCT and confocal scanning opthalmoscopy system for imaging the human eye fundus in vivo in the 1050 nm region. The instrument allows the visualization of choroidal blood vessels in both the confocal and OCT channels without the use of contrast agents such as indocyanine green (ICG) dye and could prove an alternative tool for diagnosing eye conditions like age related macular degeneration that are preceded by choroidal neovascularisation.

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Radu G. Cucu, John A. Rogers, Mark W. Hathaway, Justin Pedro, Adrian Gh. Podoleanu, and Richard B. Rosen M.D. "Combined confocal/en face optical coherence tomography imaging of the human eye fundus in vivo in the 1050 nm spectral region", Proc. SPIE 6429, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI, 642903 (7 February 2007); https://doi.org/10.1117/12.704320

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