A new apparatus for serial crystallography at the Advanced Light Source

David Shapiro; R. Bruce Doak; John Spence; Dmitri Starodub; Uwe Weierstall; Henry Chapman

doi:10.1117/12.680785

7 September 2006 A new apparatus for serial crystallography at the Advanced Light Source

David Shapiro, R. Bruce Doak, John Spence, Dmitri Starodub, Uwe Weierstall, Henry Chapman

Proceedings Volume 6318, Developments in X-Ray Tomography V; 63180L (2006) https://doi.org/10.1117/12.680785
Event: SPIE Optics + Photonics, 2006, San Diego, California, United States

Abstract

We have designed and commissioned an apparatus for serial crystallography of hydrated proteins at the Advanced Light Source. Serial crystallography is a recently proposed method of imaging uncrystallized proteins at a third generation synchrotron source. This paper describes the design of the apparatus and results from the first experiment, which recorded x-ray diffraction patterns from 8 micron droplets containing photosystem 1 protein molecules.

Citation Download Citation

David Shapiro, R. Bruce Doak, John Spence, Dmitri Starodub, Uwe Weierstall, and Henry Chapman "A new apparatus for serial crystallography at the Advanced Light Source", Proc. SPIE 6318, Developments in X-Ray Tomography V, 63180L (7 September 2006); https://doi.org/10.1117/12.680785

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