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Analysis of fluorescence spectra of polycyclic aromatic hydrocarbons in human blood plasma and human serum
albumin solution allowed one to conclude that pyrene and also anthracene are predominantly distributed in the
hydrophobic micro-phase of blood plasma proteins. In the solution of human blood plasma containing pyrene the
nonmonotonic dependence of both the intensity of pyrene fluorescence and the index of polarity on the concentration of
sodium dodecylsulfate added was observed. This should be connected with the reconstruction of the structure of protein
globule under the surfactant action and cannot be explained only by the solubilization of pyrene in sodium
dodecylsulfate micelles.
A. G. Melnikov,A. B. Pravdin,V. I. Kochubey, andG. V. Melnikov
"Spectral studies of polycyclic aromatic hydrocarbon interaction with human blood plasma", Proc. SPIE 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII, 61631H (24 July 2006); https://doi.org/10.1117/12.697351
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A. G. Melnikov, A. B. Pravdin, V. I. Kochubey, G. V. Melnikov, "Spectral studies of polycyclic aromatic hydrocarbon interaction with human blood plasma," Proc. SPIE 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII, 61631H (24 July 2006); https://doi.org/10.1117/12.697351