Evaluation of an algorithm for simultaneous reconstruction of activity and attenuation in 3D PET

Juan L. P. Soto; Sergio S. Furuie

doi:10.1117/12.653471

2 March 2006 Evaluation of an algorithm for simultaneous reconstruction of activity and attenuation in 3D PET

Juan L. P. Soto, Sergio S. Furuie

Proceedings Volume 6142, Medical Imaging 2006: Physics of Medical Imaging; 61424S (2006) https://doi.org/10.1117/12.653471
Event: Medical Imaging, 2006, San Diego, California, United States

Abstract

The main goal of this work is the performance evaluation of a tomographic reconstruction algorithm that estimates activity and attenuation images of the object of interest based only upon projections obtained from a regular Nuclear Medicine exam, without need of additional measurements. This evaluation was carried out for three-dimensional positron emission tomography, and for that purpose we used a number of numerical phantoms with random features; computer simulations that model realistically the physical processes inherent to Nuclear Medicine data acquisitions, through Monte Carlo techniques; and a comparison of the images yielded by the simultaneous reconstruction method with those provided by some of the most common tomographic reconstruction algorithms. This comparison was performed with use of figures of merit related to clinical applications, and of statistical significance tests over a large number of reconstructed objects. It was observed that this new method appears as an interesting alternative to the reconstruction methods currently in use, with promising improvement possibilities, even though fully satisfactory results are yet to be obtained.

Citation Download Citation

Juan L. P. Soto and Sergio S. Furuie "Evaluation of an algorithm for simultaneous reconstruction of activity and attenuation in 3D PET", Proc. SPIE 6142, Medical Imaging 2006: Physics of Medical Imaging, 61424S (2 March 2006); https://doi.org/10.1117/12.653471

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KEYWORDS

Reconstruction algorithms

Signal attenuation

Positron emission tomography

Monte Carlo methods

Optical spheres

3D image reconstruction

3D modeling

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