Discrete tomography from micro-CT data: application to the mouse trabecular bone structure

K. J. Batenburg; J. Sijbers

doi:10.1117/12.652603

2 March 2006 Discrete tomography from micro-CT data: application to the mouse trabecular bone structure

K. J. Batenburg, J. Sijbers

Proceedings Volume 6142, Medical Imaging 2006: Physics of Medical Imaging; 614240 (2006) https://doi.org/10.1117/12.652603
Event: Medical Imaging, 2006, San Diego, California, United States

Abstract

Discrete Tomography (DT) deals with the reconstruction of an image from its projections when this image is known to have only a small number of gray values. The knowledge of the discrete set of gray values can significantly reduce the number of projections required for a high-quality reconstruction. In this paper, a feasibility study is presented of the application of discrete tomography to micro-CT data from a mouse leg as to study the structural properties of the trabecular bone. The set of gray values is restricted to only three values, for the air background, the soft tissue background, and the trabecular bone structure. Reconstructions of the trabecular bone structure are usually obtained by computing a continuous reconstruction. To extract morphometric information from the reconstruction, the image must be segmented into the different tissue types, which is commonly done by thresholding. In the DT approach such a segmentation step is no longer necessary, as the reconstruction already contains a single gray value for each tissue type. Our results show that by using discrete tomography, a much better reconstruction of the trabecular bone structure can be obtained than by thresholding a continuous reconstruction from the same number of projections.

Citation Download Citation

K. J. Batenburg and J. Sijbers "Discrete tomography from micro-CT data: application to the mouse trabecular bone structure", Proc. SPIE 6142, Medical Imaging 2006: Physics of Medical Imaging, 614240 (2 March 2006); https://doi.org/10.1117/12.652603

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available