Paper
2 March 2006 First attempt of the medical application of the refraction-based computed tomography
Anton Maksimenko, Eiko Hashimoto, Masami Ando, Hiroshi Sugiyama, Tetsuya Yuasa
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Abstract
In recent years, the X-ray refraction contrast was widely developed and applied in different fields of science which deal with the nondestructive observation methods. As it follows from the name, the refraction contrast is the distribution of the X-ray intensity dependent on the deflection angle of the X-ray beam. This property of the contrast provides certain advantages over other contrasts such as absorption and phase-shift. The refraction contrast can show tiny details of the inner structure which are invisible in other types of the X-ray imaging techniques. Another advantage of the X-ray refraction contrast is the sensitivity to the low Z materials. This property of the refraction contrast may be of great importance in the medical applications of the X-ray. The advantages provided by the refraction contrast allow one to expect the same advantages of the computed tomography (CT) from the refraction contrast. Therefore this report is dedicated to the realization of the refraction-based CT. It describes the theoretical background of the problem, experimental realization of the method and actual results of the reconstruction of the breast cancer sample. The experimental data were acquired using X-ray synchrotron source at Photon Factory (KEK, Japan). The energy of used in the experiment was 11.7keV. The spatial resolution of the reconstructed images is about 20 microns.
© (2006) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Anton Maksimenko, Eiko Hashimoto, Masami Ando, Hiroshi Sugiyama, and Tetsuya Yuasa "First attempt of the medical application of the refraction-based computed tomography", Proc. SPIE 6142, Medical Imaging 2006: Physics of Medical Imaging, 61423Q (2 March 2006); https://doi.org/10.1117/12.652036
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KEYWORDS
Refraction

X-rays

X-ray computed tomography

Absorption

Computed tomography

Breast cancer

X-ray imaging

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