In vivo imaging polarimeter for oral precancer detection

Jungrae Chung; Woonggyu Jung; Petra Wilder-Smith; Zhongping Chen

doi:10.1117/12.589401

28 April 2005 In vivo imaging polarimeter for oral precancer detection

Jungrae Chung, Woonggyu Jung, Petra Wilder-Smith, Zhongping Chen

Proceedings Volume 5693, Optical Tomography and Spectroscopy of Tissue VI; (2005) https://doi.org/10.1117/12.589401
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

The Mueller matrix describes all the polarizing properties of a sample, and therefore the optical differences between non-cancerous and pre-cancerous tissue should be present within the matrix elements. We present in this paper that a high speedpolarimetry system generates 16 full Mueller matrices to characterize tissues. Feature extraction is done on the Mueller matrix elements resulting in the depolarizance and retardance images by polar decomposition to detect and classify of early oral cancers and pre-cancerous changes in epithelium, such as dysplasia. These images are compared with orthogonal polarization image and analyzed in an attempt to determine the important factors for the identification of cancerous lesions from their benign counterparts. Our results indicate that polarimetry has potential as a method for the in vivo early detection and diagnosis of oral premalignancy and malignancy.

Citation Download Citation

Jungrae Chung, Woonggyu Jung, Petra Wilder-Smith, and Zhongping Chen "In vivo imaging polarimeter for oral precancer detection", Proc. SPIE 5693, Optical Tomography and Spectroscopy of Tissue VI, (28 April 2005); https://doi.org/10.1117/12.589401

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available