Three-dimensional polarization-sensitive imaging of human retina in vivo with phase-resolved transversal OCT

Christoph K. Hitzenberger; Michael Pircher; Erich Goetzinger; Rainer Andreas Leitgeb; Harald Sattmann; Oliver Findl

doi:10.1117/12.592408

13 April 2005 Three-dimensional polarization-sensitive imaging of human retina in vivo with phase-resolved transversal OCT

Christoph K. Hitzenberger, Michael Pircher, Erich Goetzinger, Rainer Andreas Leitgeb, Harald Sattmann, Oliver Findl

Author Affiliations +

Proceedings Volume 5690, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX; (2005) https://doi.org/10.1117/12.592408
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

Polarization sensitive optical coherence tomography (PS-OCT) extends the concept of OCT to obtain additional information on the polarizing properties of tissue. Recently, we reported on a PS-OCT system based on transversal scanning of the probing beam across the sample, and operating at a center wavelength of 1310 nm. We now modified the instrument to allow imaging of the human retina in vivo. The instrument uses an SLD light source centered at 824 nm (FWHM bandwidth: 33 nm). A stable carrier frequency is generated by acousto optic modulators. A two-channel polarization sensitive detection unit is used to obtain amplitude and phase of the interference signals in two orthogonal polarization channels. This allows to measure and image three parameters simultaneously: reflectivity, retardation, and birefringent axis orientation. The instrument can be operated in different ways: 2D imaging along x-z or y-z planes (B-scans), along the x-y plane (C-scan), and 3D imaging are possible. Compared to our previous instrument, the imaging speed was increased by an order of magnitude. This allowed to record in vivo PS-OCT images in the fovea and nerve head region of healthy volunteers.

Citation Download Citation

Christoph K. Hitzenberger, Michael Pircher, Erich Goetzinger, Rainer Andreas Leitgeb, Harald Sattmann, and Oliver Findl "Three-dimensional polarization-sensitive imaging of human retina in vivo with phase-resolved transversal OCT", Proc. SPIE 5690, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX, (13 April 2005); https://doi.org/10.1117/12.592408

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available