A performance-optimized optical fiber bio-probe for cancerous tissue characterization

Chan Kyu Kim; Sunil K. Khijwania III; Jagdish P. Singh

doi:10.1117/12.571489

14 December 2004 A performance-optimized optical fiber bio-probe for cancerous tissue characterization

Chan Kyu Kim, Sunil K. Khijwania III, Jagdish P. Singh

Proceedings Volume 5589, Fiber Optic Sensor Technology and Applications III; (2004) https://doi.org/10.1117/12.571489
Event: Optics East, 2004, Philadelphia, Pennsylvania, United States

Abstract

Auto fluorescence of tissue depends not only on the concentration of fluoro-phores present in tissues but also on the configuration of optical fiber sensor. In this paper, feasibility of using laser induced fluorescence spectroscopy as a diagnostic tool for distinguishing malignant animal tissue from its normal counterpart under various design configurations is explored. Three different design configurations are tested for the performance optimization. The optimized Y-shaped optical reflection fiber probe gives the best laser induced fluorescence signal comparing to other probes. This instrument incorporated a continuous wave (CW) Nd:YAG laser operating at 532 nm.

Citation Download Citation

Chan Kyu Kim, Sunil K. Khijwania III, and Jagdish P. Singh "A performance-optimized optical fiber bio-probe for cancerous tissue characterization", Proc. SPIE 5589, Fiber Optic Sensor Technology and Applications III, (14 December 2004); https://doi.org/10.1117/12.571489

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