Determination of bone structural parameters from multiple projection DXA images

Thomas S. Spisz; Thomas J. Beck; Howard S. Feldmesser; Michelle H. Chen; Thomas C. Magee; Paul R. Bade; Harry K. Charles Jr.

doi:10.1117/12.535361

30 April 2004 Determination of bone structural parameters from multiple projection DXA images

Thomas S. Spisz, Thomas J. Beck, Howard S. Feldmesser, Michelle H. Chen, Thomas C. Magee, Paul R. Bade, Harry K. Charles Jr.

Author Affiliations +

Proceedings Volume 5369, Medical Imaging 2004: Physiology, Function, and Structure from Medical Images; (2004) https://doi.org/10.1117/12.535361
Event: Medical Imaging 2004, 2004, San Diego, California, United States

Abstract

To more precisely measure and monitor bone health, The Johns Hopkins University Applied Physics Lab and School of Medicine have developed the Advanced Multiple Projection Dual-Energy X-Ray Absorptiometry (AMPDXA) scanner. This system provides improvements over conventional DXA scanners in image resolution and multiple projection capability. These improvements allow us to determine structural information about the bone in addition to the standard bone mineral density (BMD) measurements. Algorithms and software were developed to process data acquired from the AMPDXA scanner and to determine important structural parameters, such as the center of mass axis in three dimensions and cross-sectional moments of inertia. The analysis operates on three projections about 15 degrees apart, calculates BMD for each projection, and then combines the data into a three dimensional coordinate system. By knowing the patient position in three dimensions, bone structural parameters are calculated more precisely. Using repeated testing of cadaver bones, the precision of determining these structural parameters is approximately the detector pixel size of 0.127 mm. Data on artificial bone cylinders indicate accuracy of about 3%. Comparisons between bone structural parameters derived from AMPDXA and CT scans show very similar results.

Citation Download Citation

Thomas S. Spisz, Thomas J. Beck, Howard S. Feldmesser, Michelle H. Chen, Thomas C. Magee, Paul R. Bade, and Harry K. Charles Jr. "Determination of bone structural parameters from multiple projection DXA images", Proc. SPIE 5369, Medical Imaging 2004: Physiology, Function, and Structure from Medical Images, (30 April 2004); https://doi.org/10.1117/12.535361

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available