Lab-on-a-chip optical detection system using plastic fiber optics

James N. McMullin; H. Qiao; Sanket Goel; S. A. McColman; A. Grundmann

doi:10.1117/12.543333

15 December 2003 Lab-on-a-chip optical detection system using plastic fiber optics

James N. McMullin, H. Qiao, Sanket Goel, S. A. McColman, A. Grundmann

Proceedings Volume 5260, Applications of Photonic Technology 6; (2003) https://doi.org/10.1117/12.543333
Event: Applications of Photonic Technology, 2003, Quebec City, Québec, Canada

Abstract

A new optical detection system for microfluidic lab-on-a-chip applications is described. The photomultiplier tube (PMT) system is controlled by LabVIEW and has output/primary current gains that are programmable from 10⁴ to 10⁷. Light is delivered to and from microfluidic systems by a custom launch-and-detect fiber probe fabricated from one-millimeter plastic optical fibers. The noise characteristics are descrbied and the detection of fluorescent 15μm polystyrene spheres is demonstrated. Using the measured static spatial response of the tip, the velocities of moving microparticles can be calculated from dynamic measurements of their fluorescence.

Citation Download Citation

James N. McMullin, H. Qiao, Sanket Goel, S. A. McColman, and A. Grundmann "Lab-on-a-chip optical detection system using plastic fiber optics", Proc. SPIE 5260, Applications of Photonic Technology 6, (15 December 2003); https://doi.org/10.1117/12.543333

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