Contrast-enhanced refraction imaging

Christopher J. Hall; Keith D. Rogers; Rob A. Lewis; Ralf Hendrik Menk; Fulvia Arfelli; Karen Kit-Wan Siu; A. Benci; M. Kitchen; Alessandra Pillon; Luigi Rigon; Andrew J. Round; Alan P. Hufton; Andrew Evans; Sarah E. Pinder; S. Evans

doi:10.1117/12.515135

30 December 2003 Contrast-enhanced refraction imaging

Christopher J. Hall, Keith D. Rogers, Rob A. Lewis, Ralf Hendrik Menk, Fulvia Arfelli, Karen Kit-Wan Siu, A. Benci, M. Kitchen, Alessandra Pillon, Luigi Rigon, Andrew J. Round, Alan P. Hufton, Andrew Evans, Sarah E. Pinder, S. Evans

Author Affiliations +

Proceedings Volume 5199, Penetrating Radiation Systems and Applications V; (2003) https://doi.org/10.1117/12.515135
Event: Optical Science and Technology, SPIE's 48th Annual Meeting, 2003, San Diego, California, United States

Abstract

An attempt has been made, for the first time, to extend the capabilities of diffraction enhanced imaging (DEI) using low concentrations of a contrast agent. A phantom has been constructed to accommodate a systematic series of diluted bromine deoxyuridase (BrDU) samples in liquid form. This was imaged using a conventional DEI arrangement and at a range of energies traversing the Br K-edge. The images were analyzed to provide a quantitative measure of contrast as a function of X-ray energy and (BrDU) concentration. The results indicate that the particular experimental arrangement was not optimized to exploit the potential of this contrast enhancement and several suggestions are discussed to improve this further.

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Christopher J. Hall, Keith D. Rogers, Rob A. Lewis, Ralf Hendrik Menk, Fulvia Arfelli, Karen Kit-Wan Siu, A. Benci, M. Kitchen, Alessandra Pillon, Luigi Rigon, Andrew J. Round, Alan P. Hufton, Andrew Evans, Sarah E. Pinder, and S. Evans "Contrast-enhanced refraction imaging", Proc. SPIE 5199, Penetrating Radiation Systems and Applications V, (30 December 2003); https://doi.org/10.1117/12.515135

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