Study of laser-induced serum Raman spectrum of esophageal cancer diagnosis and DNA measure

Xiaozhou Li; Junxiu Lin; Huiqiang Jin

doi:10.1117/12.501056

8 October 2003 Study of laser-induced serum Raman spectrum of esophageal cancer diagnosis and DNA measure

Xiaozhou Li, Junxiu Lin, Huiqiang Jin

Proceedings Volume 5141, Diagnostic Optical Spectroscopy in Biomedicine II; (2003) https://doi.org/10.1117/12.501056
Event: European Conferences on Biomedical Optics 2003, 2003, Munich, Germany

Abstract

Based on thousands cases, the discrimination in auto fluorescence Raman spectra between serum of normal human and cancer patients are found. The criteria for diagnosing cancer are also obtained after statistical analysis over experiment results. The accuracy of serum spectrum detecting results of esophageal cancer human is 82.7%. In addition, we find the resonate Raman frequency of guanine base in DNA sample depending on ultraviolet resonate Raman spectrum. The resonant Raman shifts of guanine base in DNA sample are 1337cm^-1 and 1485cm^-1 . And the resonant wave-length is 250nm.

Citation Download Citation

Xiaozhou Li, Junxiu Lin, and Huiqiang Jin "Study of laser-induced serum Raman spectrum of esophageal cancer diagnosis and DNA measure", Proc. SPIE 5141, Diagnostic Optical Spectroscopy in Biomedicine II, (8 October 2003); https://doi.org/10.1117/12.501056

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