CT perfusion: comparison of gamma-variate fit and deconvolution

Zhong Min Lin; Scott Pohlman; A. J. Cook II; Shalabh Chandra

doi:10.1117/12.463572

24 April 2002 CT perfusion: comparison of gamma-variate fit and deconvolution

Zhong Min Lin, Scott Pohlman, A. J. Cook II, Shalabh Chandra

Proceedings Volume 4683, Medical Imaging 2002: Physiology and Function from Multidimensional Images; (2002) https://doi.org/10.1117/12.463572
Event: Medical Imaging 2002, 2002, San Diego, California, United States

Abstract

The purpose of this paper is to present results of a study comparing CT brain perfusion image calculated using the maximum slope and deconvolution method on data from 32 patients. The 32 patients were organized into two groups. One group was obtained using a 4cc/sec contrast injection rate and 10 sec injection period; the other group was obtained using a 6cc/sec injection rate and 7 sec injection period. All clinical data were analyzed using both the maximum slope and deconvolution methods. Perfusion maps computed from the two methods were reviewed by radiologists. The contrast enhanced CT data were noisy, especially in the white matter area. Our results showed that, for both methods, perfusion maps from 4cc/sec injection were noisier than those using a 6cc/sec injection. However, both 4cc/sec and 6cc/sec produced useful diagnostic images. Our qualitative side-by-side studies also showed that perfusion images from the maximum slope and deconvolution are both clinically useful and substantially equivalent.

Citation Download Citation

Zhong Min Lin, Scott Pohlman, A. J. Cook II, and Shalabh Chandra "CT perfusion: comparison of gamma-variate fit and deconvolution", Proc. SPIE 4683, Medical Imaging 2002: Physiology and Function from Multidimensional Images, (24 April 2002); https://doi.org/10.1117/12.463572

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