Intrastromal refractive sugery with ultrashort laser pulses in living animals

Alexander Heisterkamp; Thanongsak Mamom; Omid Kermani; Wolfgang Drommer; Herbert Welling; Wolfgang Ertmer; Holger Lubatschowski

doi:10.1117/12.470587

13 June 2002 Intrastromal refractive sugery with ultrashort laser pulses in living animals

Alexander Heisterkamp, Thanongsak Mamom, Omid Kermani, Wolfgang Drommer, Herbert Welling, Wolfgang Ertmer, Holger Lubatschowski

Author Affiliations +

Proceedings Volume 4611, Ophthalmic Technologies XII; (2002) https://doi.org/10.1117/12.470587
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

In order to perform refractive surgery, fs-laser pulses of 130-fs pulse duration were focused into animal cornea. By focusing the radiation down to spot-sizes of 5 micrometers , very precise cuts could be achieved inside the treated eyes, accompanied with minimum collateral damage to the tissue by thermal or mechanical effects. Due to these low side effects, micrometers -cutting precisions at preparing of corneal flaps and lenticules can be achieved. Thus, animal studies with 8 living rabbits were performed, in which intrastromal lenticules and flaps were created and extracted. Wound healing reactions were studied by histo- pathological analysis of the treated eyes in intervals at one, 7, 14 and 28 days after surgery. The treated eyes showed mild wound healing reactions with comparable results to what is known from Excimer-LASIK. Moreover the use of the fs-laser offered new possibilities in preparation of corneal flaps, providing advantages to the use of the mechanical keratome.

Citation Download Citation

Alexander Heisterkamp, Thanongsak Mamom, Omid Kermani, Wolfgang Drommer, Herbert Welling, Wolfgang Ertmer, and Holger Lubatschowski "Intrastromal refractive sugery with ultrashort laser pulses in living animals", Proc. SPIE 4611, Ophthalmic Technologies XII, (13 June 2002); https://doi.org/10.1117/12.470587

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