Assessing And Neutralizing Systematic Noise Effects In Cardiac Function Quantifiers

R Luypaert; A Bossuyt; R Lepoudre

doi:10.1117/12.939330

15 June 1984 Assessing And Neutralizing Systematic Noise Effects In Cardiac Function Quantifiers

R Luypaert, A Bossuyt, R Lepoudre

Proceedings Volume 0454, Application of Optical Instrumentation in Medicine XII; (1984) https://doi.org/10.1117/12.939330
Event: Application of Optical Instrumentation in Medicine XII, 1984, San Diego, United States

Abstract

Objective interpretation of space and time dependent data as encountered in nuclear ventriculography necessitates drastic data reduction, leading to cardiac function quantifiers. Since the original data contain counting fluctuations in addition to clinical information, it seems legitimate to ask how the derived quantities are affected by the counting noise. This question is addressed here for the case of noise induced systematic errors in parameters based on activity-extrema. A computer model of the observed time-activity curves (TACs) is constructed using a truncated Fourier representation of the noise-free TACs and additive, gaussian noise. In its context a quantitative study of the noise-dependence leads to parametrizations of the systematic effects. A strategy for neutralizing the systematic errors, based on these results, is proposed and tested. It is found to be effective in both simulated and clinical environments.

Citation Download Citation

R Luypaert, A Bossuyt, and R Lepoudre "Assessing And Neutralizing Systematic Noise Effects In Cardiac Function Quantifiers", Proc. SPIE 0454, Application of Optical Instrumentation in Medicine XII, (15 June 1984); https://doi.org/10.1117/12.939330

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