Laser beam and tissue interactions: use of advanced therapeutic and diagnostic techniques: in-vitro experiments and in-vivo trials

Alexander A. Serafetinides

doi:10.1117/12.425166

9 April 2001 Laser beam and tissue interactions: use of advanced therapeutic and diagnostic techniques: in-vitro experiments and in-vivo trials

Alexander A. Serafetinides

Author Affiliations +

Proceedings Volume 4397, 11th International School on Quantum Electronics: Laser Physics and Applications; (2001) https://doi.org/10.1117/12.425166
Event: 11th International School on Quantum Electronics: Laser Physics and Applications, 2000, Varna, Bulgaria

Abstract

The mechanism of laser beam and tissue interaction is governed by the technical characteristics of the laser beam and the optical properties of the tissue. The therapeutic laser wavelength, pulse duration and beam quality, as well as the laser radiation delivery systems, the ablation mechanisms and the diagnostic techniques to monitor a surgical process are studied in this work. Advanced therapeutic and diagnostic techniques, such as integrating sphere, atomic force microscopy and beam profiling are used in the experimental study. In vitro experiments on tissue, laser ablation and diagnosis using laser induced fluorescence are performed. Finally, in vivo animal trials of an endoscopic/laparoscopic laser prototype are realized, in the framework of the appropriate protocols.

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Alexander A. Serafetinides "Laser beam and tissue interactions: use of advanced therapeutic and diagnostic techniques: in-vitro experiments and in-vivo trials", Proc. SPIE 4397, 11th International School on Quantum Electronics: Laser Physics and Applications, (9 April 2001); https://doi.org/10.1117/12.425166

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