We propose a new approach of patient-specific simulation and planning of vascular interventions using standard CT data. It is based on the virtual environment developed for the exploratory navigation within 3D volume images. Tools actions involved in the considered minimal invasive procedure have been analyzed and we present the basis of a methodological framework for the simulation of particular endovascular procedure, i.e. the artery wall expansion using a non- compliant balloon. We especially describe the characterization step, which concerns the accurate and automatic detection of the internal wall of the vessel, the description of the lumen surface, the extraction of a region of interest and the analysis of the parietal quality including the lesion. A preliminary surface model of the tool, interacting with a volume representation of the vessel wall, has been introduced in order to predict the plaque behavior during the surgical procedure. Thus, the ideal surface of the lumen and the final shape of the vessel as well as the optimal tool parameters (size, position) taking into account the lesion characteristics could be computed in the simulation process to perform actually a patient-specific planning of intervention.
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