Multimodal multispectral imaging of the cervix in vivo for the detection of neoplasia

Anant Agrawal; Tim Harrell; Shabbir B. Bambot; Mark Faupel; Daron Ferris

doi:10.1117/12.432482

2 July 2001 Multimodal multispectral imaging of the cervix in vivo for the detection of neoplasia

Anant Agrawal, Tim Harrell, Shabbir B. Bambot, Mark Faupel, Daron Ferris

Proceedings Volume 4259, Biomarkers and Biological Spectral Imaging; (2001) https://doi.org/10.1117/12.432482
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Optical spectroscopy has been shown to be an effective method for detecting neoplasia of epithelial tissues. Most studies to date in this realm have applied fluorescence or reflectance spectroscopy alone as a preferred method of disease detection. We have been developing instrumentation which can acquire both reflectance and fluorescence images of the human cervix in vivo, with the goal of combining multispectral information from the two spectroscopic modalities. This instrumentation has been tested on a group of patients in a clinical setting. We have applied spectral and spatial analysis techniques to the acquired images to assess the capabilities of this technology to discriminate neoplastic from normal cervical tissue.

Citation Download Citation

Anant Agrawal, Tim Harrell, Shabbir B. Bambot, Mark Faupel, and Daron Ferris "Multimodal multispectral imaging of the cervix in vivo for the detection of neoplasia", Proc. SPIE 4259, Biomarkers and Biological Spectral Imaging, (2 July 2001); https://doi.org/10.1117/12.432482

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