Excimer laser lead extraction catheter with increased laser parameters

M. Sean Coe; Kevin D. Taylor; Rebecca A. Lippincott; Oleg Sorokoumov M.D.; Thanassis Papaioannou

doi:10.1117/12.427834

21 May 2001 Excimer laser lead extraction catheter with increased laser parameters

M. Sean Coe, Kevin D. Taylor, Rebecca A. Lippincott, Oleg Sorokoumov M.D., Thanassis Papaioannou

Proceedings Volume 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI; (2001) https://doi.org/10.1117/12.427834
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

A fiber optic catheter connected to a pulsed excimer laser (308 nm) is currently used to extract chronically implanted pacemaker and defibrillator leads at Fluence of 60 mJ/mm² and repetition rate of 40 Hz. The object of this study was to determine the effect of higher repetition rates (80 Hz) in the catheter's cutting performance. The penetration rate (micrometers /sec), and the associated mechanical and thermal effects were measured in soft (porcine myocardium) and hard tissue (bovine tendon) at 60 mJ/mm²-80 Hz, and were compared to the corresponding values at commercially available laser parameters (60 mJ/mm²-40 Hz). Ablation rates were measured with perforation experiments and the extent of thermal and mechanical damage was measured under polarized light microscopy. For hard (soft) tissue, the laser catheter demonstrated penetration speed of 106 +/- 32 (302 +/- 101) micrometers /sec at 40 Hz and 343 +/- 120 (830 +/- 364) micrometers /sec at 80 Hz. Maximum extent of thermal effects at 40 Hz and 80 Hz was 114 +/- 35 micrometers (72 +/- 18) and 233 +/- 63 micrometers (71 +/- 16) respectively. Maximum extent of mechanical effects at 40 Hz and 80 Hz was 188 +/- 63 micrometers (590 +/- 237) and 386 +/- 100 micrometers (767 +/- 160) respectively. In vitro testing of the laser catheter with 80 Hz laser parameters has demonstrated increased penetration speed in both soft and hard fibrous tissue, while maintaining associated thermal and mechanical effects within limited ranges.

Citation Download Citation

M. Sean Coe, Kevin D. Taylor, Rebecca A. Lippincott, Oleg Sorokoumov M.D., and Thanassis Papaioannou "Excimer laser lead extraction catheter with increased laser parameters", Proc. SPIE 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI, (21 May 2001); https://doi.org/10.1117/12.427834

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